Jutta Gärtner

Professor, German Primate Center

• 1988 - 1991 Postdoctoral Fellow, Kennedy Krieger Institute for Handicapped Children, Johns Hopkins School of Medicine Baltimore, U.S.A.

• 1989 Summer School Student in Molecular Biology, Jackson Laboratory Bar Harbor and Johns Hopkins University Baltimore, U.S.A.

• 1990 - 1991 Postdoctoral Fellow, Howard Hughes Medical Institute, Johns Hopkins School of Medicine Baltimore, U.S.A.

• 1991 - 1993 Instructor and Faculty Member, Department of Pediatrics, Johns Hopkins School of Medicine Baltimore, U.S.A.

• 1993 - 1995 Research Fellow, Department of Pediatrics, University of Düsseldorf

• 1995 - 2000 Ass. Professor, Dept. of Pediatrics, University of Düsseldorf

• 2000 - 2002 University Professor, Department of Pediatrics and Pediatric Neurology, University of Düsseldorf

• since 2002 University Professor and Chair, Department of Pediatrics and Pediatric Neurology, University of Göttingen

Major Research Interests:

Jutta Gärtner

Molecular basis of peroxisome biogenesis: peroxisomal membrane proteins and their role in peroxisome assembly and function Peroxisomal disorders: Clinical and molecular characterization of patients with peroxisome biogenesis disorders and X-linked adrenoleukodystrophy Leukodystrophies: Clinical, neuroradiological and molecular characterization of patients with unclassified leukodystrophies

Address:
Department of Pediatrics and Pediatric Neurology
University of Göttingen
Robert-Koch-Str. 40
37075 Göttingen
Germany

phone: +49-551-39 8035
fax: +49-551-39 6252
e-mail:

Further Information:
Department Research Group

Selected Recent Publications:

Roerig P, Mayerhofer P, Holzinger A, Gärtner J (2001): Characterization and functional analysis of the nucleotide binding fold in human peroxisomal ATP-binding cassette transporters. FEBS Lett 24674:1-7.

Brosius U, Dehmel, T, Gärtner J (2002): Two different targeting signals direct human PMP22 to peroxisomes. J Biol Chem 277:774-784.

Steinfeld R, Steinke HB, Isbrandt D, Kohlschütter A, Gärtner J (2004): Mutations in classical late infantile neuronal ceroid lipofuscinosis disrupt transport of tripeptidyl-peptidase I to lysosomes. Hum Mol Genet 13:2483-2491.

Uhlenberg B, Schuelke M, Ruschendorf F, Ruf N, Kaindl AM, Henneke M, Thiele H, Stoltenburg-Didinger G, Aksu F, Topaloglu H, Nürnberg P, Hübner C, Weschke B, Gärtner J (2004): Mutations in the gene encoding gap junction protein alpha 12 (connexin 46.6) cause Pelizaeus-Merzbacher-like disease. Am J Hum Genet 75:251-260.

Steinfeld R, Reinhardt K, Schreiber K, Hillebrand M, Kraetzer R, Brück W, Saftig P, Gärtner J (2006): Cathepsin D deficiency is associated with a human neurodegenerative disorder. Am J Hum Genet 78: 988-989.